The chloroform extract of the leaves of Caesalpinia pyramidalis (Caesalpinioidea , Fabaceae) yielded the new biflavonoid named caesalflavone, as well as. Recebido em 17/9/09; aceito em 2/2/10; publicado na web em 18/6/10 The chloroform partition of methanol extract of leaves of Caesalpinia. PDF | The chloroform extract of the leaves of Caesalpinia pyramidalis ( Caesalpinioidea, Fabaceae) yielded the new biflavonoid named caesalflavone, as well as.

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The extract was filtered and caeslpinia for bioassay analysis. The position of the methoxyl group was established by UV spectral analysis with the AlCl 3 reagent shift. Its control based on the use of commercial anthelmintics is no longer considered sustainable due to an increased prevalence of GIN resistance as well as chemical residue and toxicity problems [ 2 ].

This concentration appears to be the most efficient. This work aims at evaluating the anthelmintic effect of CP extract in vivo against GIN natural infected goats in order to caesalpinnia the benefits.

Evidence-Based Complementary and Alternative Medicine

In Bahia State, it is popularly known as “catingueiro” or “pau-de-rato”, and its leaves are employed in traditional medicine as diuretic, dyspeptic, digestive, and antipyretic.

All these parameters are considered to be important element in the response against GIN infection. In the study of humoral immune response, antibodies of two immunoglobulin classes were investigated: Mean concentrations of serum IgG a and IgA b in goats naturally infected with gastrointestinal nematodes, traited with 2. We were indebted to Prof. Thus, the linkage at C-6 of the flavone unit was established due to the presence of methine carbon signals at d Subscribe to Table of Contents Alerts.

Thus, the correlations observed between caesalpiniaa peaks displayed at d 7. The existence of a 1,4-dissubstituted ring B was shown by characteristic doublets d 7. Introduction The genus Caesalpinia Caesalpinioideae, Fabaceaecomprised of tropical or subtropical trees or shrubs, contains more than species worldwide.


This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The packed cell caesalpinoa PCV was measured by the microhaematocrit method. The average values were not significantly different between the extract and Doromectin treated groups G2, G3, G4 and cwesalpinia untreated group G1. Other slight differences in resonances observed between compound 2 and literature data were attributed to the solvent employed.

To date, there are no reports in literature regarding compound 1. Nova27 Introduction Goat herding is an attractive source of income for farmers in northeastern Brazil.

Caesalpinia pyramidalis

New York,pp. Botanical material of C. In the present experiment, it is likely that another mechanism of the CP extract affects against GIN. This chalcone was previously found in C. The chloroform extract of the trunk wood gave 4,4′-dihydroxy-2′-methoxychalcone, – -syringaresinol, and methyl gallate. Goat herding is an attractive source of income for farmers in northeastern Brazil. The in vivo trials on the anthelmintic activity cawsalpinia CP extract showed significant reduction in the mean faecal egg count throughout experimental period Figure 1 a.

Once some plants have been reported to have anthelmintic properties, attributed to secondary metabolites e. However, its phytochemical analysis revealed the presence of different chemical compounds, among them polyphenols, like caesalinia and flavonoids [ 1112 ], that could be considered as the responsible for this bioactivity [ 1617 ].

Similarly, the extract does not appear to have influenced the change of weight in animal groups during caesalinia experimental period. NMR data is in agreement with mass spectrum and showed that the biflavonoid is made up of flavanone and flavone units Table 1. There are several species of plants used by traditional communities in the Brazilian semiarid. Some compounds from C. The mechanisms whereby the consumption of certain plants and plant extracts can affect parasite cycle both in vitro and in vivo are unknown.


The absence of bathochromic effect permitted to localize the methoxyl group in the C-2′. Caesalpinia pyramidalis Tul is an endemic tree of northeastern region and one of the predominant species in the “caatinga” vegetation.

In a previous work 8 on organic extracts from C. The monitoring was carried out between March and May, coinciding with the end of the dry season and beginning of the rainy period. Abstract Forty-eight goats naturally infected with gastrointestinal nematodes were randomly divided into four pytamidalis The hexane partition 7.

The genus Caesalpinia Fabaceaecomposed of tropical or subtropical trees and shrubs, pygamidalis more than species, spread throughout the world [ 7 ]. However, the analysis of HMBC spectrum data for the linkage between the flavonoid units was conclusive.

Caesalpinia pyramidalis | Caesalpinia pyramidalis is common … | Flickr

The parasitological analysis indicated that the CP extract exhibited anthelmintic activity in naturally infected goats, whose effectiveness was evidenced by the reduction in FEC as compared to the negative control group.

The egg excretion pattern was similar for the positive control G2 and treated groups G3 and G4.

From the present results and considering the significant reduction in the egg output, this study indicates that IgA may play a role in the parasite control. Material and Methods 2. The C-6 flavone linkage was also suggested by the shielded peak of the methine carbon C-8 d